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Which of the following features is NOT a risk factor associated with long-term disability in multiple sclerosis patients?
   
CME InfoHelp
Title: "Managing Disease-Modifying Therapy in Multiple Sclerosis"
Jointly Sponsored/Co-provided by: The University of Texas Southwestern Medical Center, Postgraduate Institute for Medicine, and Medical Logix, LLC
Release Date: October 24, 2013
Expiration Date: October 24, 2014
Estimated time to complete each part of this activity:   30 minutes; this activity has been approved for a maximum of 0.50 AMA PRA Category 1 Credit(TM) and 0.5 contact hours for nurses.  There are no fees or prerequisites.
Acknowledgement of Commercial Support:  Supported by independent educational grants from Genzyme, a Sanofi company and Novartis.
Learning Objectives
After participating in this activity, the participant will demonstrate the ability to:
1. Discuss factors that support the determination of a treatment failure
2. Describe circumstances when a therapeutic change is recommended
3. Explain considerations where maintenance of a current therapy is recommended
4. Compare efficacy data of available therapies for the treatment of MS
5. Compare side effect data of available therapies for the treatment of MS
6. Demonstrate an understanding of risk/benefit assessment when evaluating available therapies for the treatment of MS
7. Discuss strategies to address patient concerns regarding initiation of therapy, therapy change or maintenance of current therapy
8. Formulate a plan for the incorporation of newer therapies for the treatment of MS into clinical practice
9. Provide appropriate care and counsel for patients and their families
Statement of Need
The complexity of MS patient management is increasing dramatically, based on the growth of novel disease modifying therapy options. One of the most challenging issues to face neurologists in the coming years is the integration of these newer therapies into their clinical armamentarium. With the growing complexity of patients and intervention strategies, there exists a need for more intense continuing medical education. This patient centered CME/CNE program allows MS treating clinicians to learn in the context of actual MS patients. With new disease modifying therapies available and emerging, there is a unique opportunity to provide educational experiences in the context of real world referrals that can alter long-term practice patterns.
Intended Audience
This activity is intended for healthcare professionals, specifically, neurologists, internists, family practice physicians, nurse practitioners, physician assistants, registered nurses and other providers involved in the care of patients with multiple sclerosis.
Faculty and Disclosures
Conflict of Interest: All persons in the position to control the content of an education activity are required to disclose all relevant financial relationships in any amount occurring within the past 12 months with any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on patients.  Failure or refusal to disclose relevant financial relationships will disqualify the participant from involvement in the CME activity.  Disclosure of financial relationships includes both the faculty and their spouse/domestic partner.
Identified conflicts of interest will be resolved prior to an educational activity being delivered to learners through one of the following mechanisms 1) altering the financial relationship with the commercial interest, 2) altering the individual’s control over CME content about the products or services of the commercial interest, and/or 3) validating the activity content through independent peer review.  The faculty members' relationships are disclosed below.
Faculty:  
Benjamin M. Greenberg, MD, MHS
Deputy Director, Multiple Sclerosis Program
Director, Transverse Myelitis, Neuromyelitis Optica and Pediatric Demyelinating
Disease Program
Cain-Denius Scholar for Mobility Disorders
Department of Neurology and Neurotherapeutics
Department of Pediatrics
UT Southwestern Medical Center
Children's Medical Center
Dallas, Texas
Reviewer:
Joseph K. Vaughan, Jr., MD
Assistant Professor
Department of Neurology and Neurotherapeutics
UT Southwestern Medical Center
Dallas, Texas
Disclosures:
The following relationships have been reported for this activity:
Benjamin M. Greenberg, MD, MHS
Consultant:  Biogen Idec, Chugai, GlaxoSmithKline, Novartis, Sanofi
Ownership Interest:  Amplimmune, DioGenix
Joseph K. Vaughan, Jr., MD
Speaker:  Nautilus Neurosciences, Transdermal Therapeutics
The following Postgraduate Institute for Medicine planners and managers, Laura Excell, ND, NP, MS, MA, LPC, NCC, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CCMEP, and Jan Schultz, RN, MSN, CCMEP, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
The following Medical Logix, LLC planners/managers, John Gentile and Michael Speidel, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.  The following Medical Logix medical writer, Dorlan Kimbrough, MD has disclosed the following:
Educational Grant Support:  Teva
The following UT Southwestern employee, Anne Perch, hereby states that she or her spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
Off-label Discussions
There are no off-label discussions in this CME/CNE activity.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of The University of Texas Southwestern Medical Center and Medical Logix LLC. The University of Texas Southwestern Medical Center is accredited by the ACCME to provide continuing medical education for physicians.
Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
Credit Designation Statement
The University of Texas Southwestern Medical Center designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)TM. Participants should claim only the credit commensurate with the extent of their participation in the activity.
This educational activity for 0.5 contact hours is provided by Postgraduate Institute for Medicine.
Format and Method of Participation
There are no fees for participating and receiving CME or CNE credit for this activity. During the accreditation period, participants must read the learning objectives and faculty disclosures and review this internet-based activity. To take the post-test, please click on the post-test button below the slide window of the player. Complete the post-test and evaluation and attest to the amount of time spent in the activity. Upon receiving a score of 70% or above, print your CME or CE certificate.
For CME questions, please contact the UTSW Office of CME at (214) 648-2166.  
For CNE questions, please contact Postgraduate Institute for Medicine at: information@pimed.com or (303) 799-1930.
Technical Requirements
Processor Speed:  Dual Core with 2 GHz or above
Memory:  1024 (512MB available)
Operating Systems Supported: Win XP/windows 7 or above, MAC
Browsers Supported:  IE8 or above, Firefox 20.X or above, Safari 5.0X or above
Additional Requirements:  Flash player 9.0 or greater, 1024x768 Resolution or higher with 32-bit color
Connection Speed:  256Kbps or better
Adobe Acrobat 10.X or greater
Technical Questions:
Please click on the Help button within the online player, or email MS-Leaders at support@ms-leaders.com
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